• Genome-wide prediction and tra...

Treffer: Genome-wide prediction and transcriptome analysis of sugar transporters in four ascomycete fungi

Title:
Genome-wide prediction and transcriptome analysis of sugar transporters in four ascomycete fungi
Authors:
Xu, Li, Li, Jiajia, Gonzalez Ramos, Victor M, Lyra, Christina, Wiebenga, Ad, Grigoriev, Igor V, de Vries, Ronald P, Mäkelä, Miia R, Peng, Mao
Source:
Xu , L , Li , J , Gonzalez Ramos , V M , Lyra , C , Wiebenga , A , Grigoriev , I V , de Vries , R P , Mäkelä , M R & Peng , M 2024 , ' Genome-wide prediction and transcriptome analysis of sugar transporters in four ascomycete fungi ' , Bioresource Technology , vol. 391 , no. Pt B , pp. 130006 . https://doi.org/10.1016/j.biortech.2023.130006
Publication Year:
2024
Collection:
KNAW: Research Explorer (Koninklijke Nederlandse Akademie van Wetenschappen / Royal Netherlands Academy of Arts and Sciences)
Subject Terms:
Phylogeny, Fungal Proteins/genetics, Ascomycota/metabolism, Gene Expression Profiling, Transcriptome/genetics, Sugars
Document Type:
Fachzeitschrift article in journal/newspaper
Language:
English
DOI:
10.1016/j.biortech.2023.130006
Availability:
https://pure.knaw.nl/portal/en/publications/b1e20629-ec71-49d8-afa2-aab3b8ab98c5
https://doi.org/10.1016/j.biortech.2023.130006
https://hdl.handle.net/20.500.11755/b1e20629-ec71-49d8-afa2-aab3b8ab98c5
Rights:
info:eu-repo/semantics/openAccess
Accession Number:
edsbas.58ABEBF8
Database:
BASE

Weitere Informationen

The import of plant-derived small sugars by sugar transporters (STs) has received increasing interest due to its important biological role and great industrial potential. STs are important targets of genetic engineering to improve fungal plant biomass conversion. Comparatively analysis of the genome-wide prevalence and transcriptomics of STs was performed in four filamentous fungi: Aspergillus niger, Aspergillus nidulans, Penicillium subrubescens and Trichoderma reesei. Using phylogenetic analysis and literature mining, their predicted STs were divided into ten subfamilies with putative sugar specificities assigned. In addition, transcriptome analysis revealed complex expression profiles among different STs subfamilies and fungal species, indicating a sophisticated transcriptome regulation and functional diversity of fungal STs. Several STs showed strong co-expression with other genes involved in sugar utilization, encoding CAZymes and sugar catabolic enzymes. This study provides new insights into the diversity of STs at the genomic/transcriptomic level, facilitating their biochemical characterization and metabolic engineering.