Treffer: Local skin reaction to intramuscular administration of enrofloxacin in pythons.

Two cases of local skin reactions to intramuscular application of enrofloxacin in a reticulated python (Malayopython reticulatus) (6 years, 5.5 kg) and a Burmese python (Python bivitatus) (3 years, 25 kg) are presented. The reticulated python was treated for a swelling of the upper jaw, while the Burmese python had respiratory symptoms. The first python was treated with meloxicam for 7 days, but since the swelling did not go down, the local veterinarian consulted a reptile expert. Instead of the recommended marbofloxacin, the animal received an intramuscular injection of enrofloxacin, and swelling and a sterile abscess appeared at the injection site, with local pinkish skin discolouration. After marbofloxacin therapy was continued, the swelling disappeared. The white spotpatch at the site of the single application of enrofloxacin is still present after 3 months. The Burmese python received enrofloxacin and bromhexine hydrochloride intramuscularly for 14 days. Sterile abscesses and skin discolouration occurred at 3-4 sites of enrofloxacin application. Initially, the scales around the site of enrofloxacin application became pale and matte, later appearing as though the scales had melted or fused. Even 5 years later, a slight spherical bulge with a hard-elastic consistency can be felt. The treatment was carried out in another local clinic. Intramuscular application of enrofloxacin in pythons can lead to the formation of a sterile abscess at the injection site and long-term discolouration of the skin above that site, although some prescriptions warn of possible skin discoloration, but only after subcutaneous administration of enrofloxacin. [ABSTRACT FROM AUTHOR]

Prikazana su dva slučaja lokalne kožne reakcije na intramuskularnu primjenu enrofloksacina u mrežastog pitona (Malayopython reticulatus) (6 godina, 5,5 kg) i burmanskog pitona (Python bivitatus) (3 godine, 25 kg). Mrežastom pitonu liječena je oteklina na gornjoj čeljusti, dok je burmanski piton imao respiratorne simptome. Prvog pitona liječili su 7 dana meloksikamom, budući da oteklina nije nestala lokalni je veterinar zatražio savjet stručnjaka za gmazove s Veterinarskog fakulteta Sveučilišta u Zagrebu. Umjesto preporučenog marbocilina, životinja je liječena intramuskularnu injekciju enrofloksacina, nakon čega se pojavio otok i sterilni apsces s ružičastom lokaliziranom diskoloracijom kože. Nakon nastavka terapije marbofloksacinom otok je nestao. Bijela mrlja na mjestu jednokratne primjene enrofloksacina bila je i dalje prisutna nakon tri mjeseca. Burmanski piton primao je enrofloksacin i bromheksin hidroklorid intramuskularno 14 dana. Na 3-4 mjesta primjene enrofloksacina pojavili su se sterilni apscesi i promjena boje kože. Prvo su ljuskice oko mjesta aplikacije enrofloksacina poblijedjele i bez sjaja, a kasnije je izgledalo kao da su se ljuskice otopile ili spojile. I danas, 5 godina poslije, može se napipati blago kuglasto ispupčenje tvrdo-elastične konzistencije. Liječenje je provedeno u drugoj lokalnoj klinici. Intramuskularna primjena enrofloksacina u pitona može prouzročiti stvaranje sterilnog apscesa na mjestu uboda kao i dugotrajnu promjenu boje kože iznad toga mjesta. Neke upute upozoravaju na moguću promjenu boje kože, ali tek nakon subkutane primjene enrofloksacina. [ABSTRACT FROM AUTHOR]

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