Treffer: Exploration of alzheimer disease using design of experiments.

This study examines the use of experimental designs, specifically full and fractional factorial designs, for predicting Alzheimer's disease with fewer variables. The full factorial design systematically investigates the effects of selected factors, providing a comprehensive analysis of their individual and interactive impacts on Alzheimer's prediction. On the other hand, the fractional factorial design simplifies the model by selecting key factors and removing non-significant ones. For Alzheimer's, among all the factors examined, the MMSE (Mini-mental state Examination) score emerged as the most significant, which was further cross-validated using Minitab Software Analysis. Importantly, the findings suggest that the fractional factorial design is a better alternative, particularly when time and cost constraints are present. The results highlight the effectiveness and efficiency of these experimental designs, demonstrating their potential for early detection, prevention, and treatment of Alzheimer's disease. By contributing to the expanding knowledge base on experimental designs in medical research, this study emphasizes their crucial role in understanding and combating complex diseases like Alzheimer's. [ABSTRACT FROM AUTHOR]

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