Treffer: FedGraphHE: A privacy-preserving federated graph neural network framework with dynamic homomorphic encryption and robust aggregation.

Title:
FedGraphHE: A privacy-preserving federated graph neural network framework with dynamic homomorphic encryption and robust aggregation.
Authors:
Zuo A; School of Information and Control Engineering, Jilin University of Chemical Technology, Jilin, China., Feng Z; School of Information Engineering, Xuchang University, Xuchang, China., Ping Y; School of Information Engineering, Xuchang University, Xuchang, China., Tao S; School of Information Engineering, Xuchang University, Xuchang, China., Sun H; School of Information Engineering, Xuchang University, Xuchang, China., Chen Y; School of Information Engineering, Xuchang University, Xuchang, China.; Henan Province Engineering Technology Research Center of Big Data Security and Application, Xuchang, China.; Henan International Joint Laboratory of Polarization Sensing and Intelligent Signal Processing, Xuchang, China.
Source:
PloS one [PLoS One] 2026 Jan 05; Vol. 21 (1), pp. e0339881. Date of Electronic Publication: 2026 Jan 05 (Print Publication: 2026).
Publication Type:
Journal Article
Language:
English
Journal Info:
Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Imprint Name(s):
Original Publication: San Francisco, CA : Public Library of Science
References:
IEEE J Biomed Health Inform. 2022 Jul;26(7):3342-3353. (PMID: 35259122)
J Law Biosci. 2024 Sep 27;11(2):lsae022. (PMID: 39346780)
Sci Rep. 2024 Oct 26;14(1):25449. (PMID: 39455647)
Nat Commun. 2022 Jun 2;13(1):3091. (PMID: 35654792)
J Biomed Inform. 2024 Mar;151:104616. (PMID: 38423267)
Peer Peer Netw Appl. 2023;16(2):1257-1269. (PMID: 37152768)
Entry Date(s):
Date Created: 20260106 Date Completed: 20260106 Latest Revision: 20260109
Update Code:
20260109
PubMed Central ID:
PMC12768379
DOI:
10.1371/journal.pone.0339881
PMID:
41490270
Database:
MEDLINE

Weitere Informationen

Federated learning (FL) enables collaborative model training across distributed intelligent devices while preserving data privacy. In smart healthcare networks, medical institutions can jointly learn from distributed patient data using graph neural networks (GNNs). This approach improves diagnostic accuracy without compromising patient confidentiality. However, federated GNNs face substantial challenges. These include gradient privacy vulnerabilities, computational overhead from homomorphic encryption, and susceptibility to Byzantine attacks. This paper presents FedGraphHE, a privacy-preserving federated GNN framework for secure collaborative intelligence. Our methodology integrates three synergistic modules. First, Dynamic Adaptive Partitioned Homomorphic Encryption (DAPHE) optimizes gradient transmission. Second, Hierarchical Multi-scale Adaptive Graph Transformer (HMAGT) enables encryption-aware graph processing. Third, Federated Robust Aggregation via Homomorphic Inner Product (FRAHIP) provides Byzantine-resilient aggregation. Experimental results demonstrate FedGraphHE's effectiveness across multiple scenarios. The framework consistently outperforms existing privacy-preserving methods on citation network benchmarks (Cora, CiteSeer, PubMed). It achieves 98.18% classification accuracy on medical imaging datasets (ISIC 2020), and reduces communication costs by approximately 25% compared to existing homomorphic encryption baselines. The framework maintains over 95% accuracy under Byzantine attacks, establishing it as an effective solution for privacy-sensitive collaborative learning applications.
(Copyright: © 2026 Zuo et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)

The authors have declared that no competing interests exist.