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A 14-year old boy with pronounced facial asymmetry was referred for [ 99m Tc]Tc-3,3-diphosphono-1,2-propanodicarboxylic acid (DPD) single-photon emission computed tomography / computed tomography (SPECT/CT) of the jaw. The initial clinical suspicion of causative fibrous dysplasia in the retromolar region was ruled out through both imaging and bone biopsy. Instead, [ 99m Tc]Tc-DPD-SPECT/CT confirmed the presence of hemimandibular hyperplasia. Cinematic rendering provided photorealistic images, effectively visualizing the asymmetry of the mandible and teeth, and the underlying increased condylar bone turnover.
(Copyright © 2025 The Author(s). Published by Wolters Kluwer Health, Inc.)
Conflicts of interest and sources of funding: M.H. received grants and speaker honoraria from GE HealthCare, a fund by the Alfred and Annemarie von Sick legacy and a grant from the clinical research priority program (CRPP) Artificial Intelligence in Oncological Imaging Network of the University of Zurich.