Treffer: TVB C++: A Fast and Flexible Back-End for The Virtual Brain.
Title:
TVB C++: A Fast and Flexible Back-End for The Virtual Brain.
Authors:
Martín I; ViRVIG, Universitat de Girona, Girona, 17003, Spain., Zamora-López G; Center for Brain and Cognition, Computational Neuroscience Group, Department of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, 08005, Spain.; Department of Complex Systems, Institute of Computer Science, The Czech Academy of Sciences, Prague, 182 00, Czech Republic., Fousek J; Institut de Neurosciences des Systèmes, Aix Marseille Université, Marseille, 13005, France.; Central European Institute of Technology (CEITEC), Masaryk University, Pekařská 53, Brno, 65691, Czech Republic., Schirner M; Berlin Institute of Health, Charité - Universitätsmedizin Berlin, 10178, Berlin, Germany., Ritter P; Berlin Institute of Health, Charité - Universitätsmedizin Berlin, 10178, Berlin, Germany., Jirsa V; Institut de Neurosciences des Systèmes, Aix Marseille Université, Marseille, 13005, France., Deco G; Center for Brain and Cognition, Computational Neuroscience Group, Department of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, 08005, Spain.; Institució Catalana de la Recerca i Estudis Avançats (ICREA), Barcelona, 08010, Spain., Patow G; ViRVIG, Universitat de Girona, Girona, 17003, Spain.; Center for Brain and Cognition, Computational Neuroscience Group, Department of Information and Communication Technologies, Universitat Pompeu Fabra, Barcelona, 08005, Spain.
Source:
Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2026 Jan; Vol. 13 (2), pp. e06440. Date of Electronic Publication: 2025 Oct 17.
Publication Type:
Journal Article
Language:
English
Journal Info:
Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844 (Electronic) Linking ISSN: 21983844 NLM ISO Abbreviation: Adv Sci (Weinh) Subsets: MEDLINE
Imprint Name(s):
Original Publication: Weinheim : WILEY-VCH, [2014]-
MeSH Terms:
References:
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Front Comput Neurosci. 2023 Jan 13;16:1058957. (PMID: 36714530)
Adv Sci (Weinh). 2026 Jan;13(2):e06440. (PMID: 41103211)
Neuroimage. 2015 Aug 15;117:343-57. (PMID: 25837600)
Sci Rep. 2023 Sep 21;13(1):15698. (PMID: 37735201)
Trends Neurosci. 2016 Mar;39(3):125-135. (PMID: 26833259)
Neuroimage. 2000 Oct;12(4):466-77. (PMID: 10988040)
PLoS One. 2019 Dec 16;14(12):e0225900. (PMID: 31841550)
Neuroscientist. 2001 Apr;7(2):123-35. (PMID: 11496923)
Sci Rep. 2017 Jun 8;7(1):3095. (PMID: 28596608)
PLoS Comput Biol. 2020 Nov 30;16(11):e1008386. (PMID: 33253147)
Elife. 2019 Apr 26;8:. (PMID: 31025934)
Magn Reson Med. 1998 Jan;39(1):41-52. (PMID: 9438436)
Sci Adv. 2021 Jul 14;7(29):. (PMID: 34261652)
J Neurosci. 1996 Jul 1;16(13):4207-21. (PMID: 8753882)
Brain. 2017 Apr 1;140(4):1068-1085. (PMID: 28334882)
Curr Biol. 2018 Oct 8;28(19):3065-3074.e6. (PMID: 30270185)
Neuroimage. 2015 Jan 15;105:525-35. (PMID: 25462790)
Epilepsia. 2022 Aug;63(8):1942-1955. (PMID: 35604575)
Front Neuroinform. 2014 Apr 23;8:38. (PMID: 24795618)
Neuroimage. 2017 Jan 15;145(Pt B):377-388. (PMID: 27477535)
PLoS Comput Biol. 2022 May 18;18(5):e1009342. (PMID: 35584147)
Phys Rev Lett. 2020 Dec 11;125(24):248101. (PMID: 33412049)
Neural Comput. 2009 Jan;21(1):46-100. (PMID: 19210171)
Nat Neurosci. 2000 Nov;3(11):1153-9. (PMID: 11036274)
Elife. 2018 Jan 08;7:. (PMID: 29308767)
Nat Commun. 2022 Jun 27;13(1):3683. (PMID: 35760787)
Front Neuroinform. 2013 Jun 11;7:10. (PMID: 23781198)
Netw Neurosci. 2023 Oct 01;7(3):966-998. (PMID: 37781151)
Neuroimage. 2004 Jan;21(1):144-53. (PMID: 14741651)
Neuroimage. 2022 May 1;251:118973. (PMID: 35131433)
Neural Comput. 2019 Apr;31(4):653-680. (PMID: 30764741)
Alzheimers Res Ther. 2023 Dec 5;15(1):210. (PMID: 38053164)
Front Neuroinform. 2014 Jan 06;7:48. (PMID: 24431999)
Netw Neurosci. 2023 Jun 30;7(2):632-660. (PMID: 37397876)
J Neurophysiol. 2020 Mar 1;123(3):1042-1051. (PMID: 31851573)
Neuroimage. 2007 Nov 15;38(3):387-401. (PMID: 17884583)
J Comput Neurosci. 2006 Oct;21(2):119-29. (PMID: 16732488)
Trends Cogn Sci. 2015 Oct;19(10):616-628. (PMID: 26412099)
PLoS Comput Biol. 2019 May 9;15(5):e1007019. (PMID: 31071085)
Netw Neurosci. 2021 Aug 30;5(3):757-782. (PMID: 34746626)
Front Comput Neurosci. 2019 Aug 13;13:54. (PMID: 31456676)
Cereb Cortex. 2014 Mar;24(3):663-76. (PMID: 23146964)
Elife. 2019 Aug 20;8:. (PMID: 31429824)
Brain Connect. 2013;3(2):121-45. (PMID: 23442172)
J Neurophysiol. 2011 Sep;106(3):1125-65. (PMID: 21653723)
J Cereb Blood Flow Metab. 1997 Jan;17(1):64-72. (PMID: 8978388)
Neuroinformatics. 2024 Jan;22(1):75-87. (PMID: 37981636)
J Neurosci. 2014 Jun 4;34(23):7886-98. (PMID: 24899711)
J Comput Neurosci. 2018 Feb;44(1):45-61. (PMID: 29139050)
Grant Information:
PID2021-122136OB-C22 Ministerio de Ciencia, Innovación y Universidades; PID2022-136216NB-I00 Ministerio de Ciencia, Innovación y Universidades; 785907 (HBP SGA2) H2020 Excellent Science; Horizon EBRAINS2.0 (101147319) HORIZON EUROPE Framework Programme; Virtual Brain Twin (101137289) HORIZON EUROPE Framework Programme; EBRAINS-PREP 101079717 HORIZON EUROPE Framework Programme; AISN - 101057655 HORIZON EUROPE Framework Programme; EBRAIN-Health 101058516 HORIZON EUROPE Framework Programme; EICgrantPHRASE(101058240) HORIZON EUROPE Framework Programme; DigitalEuropeTEF-Health(101100700) HORIZON EUROPE Framework Programme; BRIDGE(101219311) HORIZON EUROPE Framework Programme; SHAIPED(101195135) HORIZON EUROPE Framework Programme; CoordinaTEF(101168074) HORIZON EUROPE Framework Programme; SFB 1436 (project ID 425899996) Kinderherzen Fördergemeinschaft Deutsche Kinderherzzentren; SFB 1315 (project ID 327654276) Kinderherzen Fördergemeinschaft Deutsche Kinderherzzentren; SFB 936 (project ID 178316478 Kinderherzen Fördergemeinschaft Deutsche Kinderherzzentren; SFB-TRR 295 (project ID 424778381) Kinderherzen Fördergemeinschaft Deutsche Kinderherzzentren; SPP Computational Connectomics RI 2073/6-1 Kinderherzen Fördergemeinschaft Deutsche Kinderherzzentren; RI 2073/10-2 Kinderherzen Fördergemeinschaft Deutsche Kinderherzzentren; RI 2073/9-1 Kinderherzen Fördergemeinschaft Deutsche Kinderherzzentren; BECAUSE-Y 504745852 DFG Clinical Research Group; CZ.02.01.01/00/22\_008/0004643 ERDF; 2021SGR00917 AGAUR; 2021SGR01035 AGAUR; 945539(HBPSGA3) Horizon 2020; 425899996 German Research Foundation; 327654276 German Research Foundation; 178316478 German Research Foundation; 424778381 German Research Foundation; RI2073/6-1 SPP Computational Connectomics; RI2073/10-2 SPP Computational Connectomics; RI2073/9-1 SPP Computational Connectomics; ANR-22-PESN-0012 Agence Nationale de la Recherche; NEMESIS(101071900) International ERC_ European Research Council
Contributed Indexing:
Keywords: C++; fast; the virtual brain; whole‐brain model
Entry Date(s):
Date Created: 20251017 Date Completed: 20260109 Latest Revision: 20260111
Update Code:
20260111
PubMed Central ID:
PMC12786347
DOI:
10.1002/advs.202406440
PMID:
41103211
Database:
MEDLINE
Weitere Informationen
This study introduces TVB C++, a streamlined and fast C++ Back-End for The Virtual Brain (TVB), a renowned platform and a benchmark tool for full-brain simulation. TVB C++ is engineered with speed as a primary focus while retaining the flexibility and ease of use characteristic of the original TVB platform. Positioned as a complementary tool, TVB serves as a prototyping platform, whereas TVB C++ becomes indispensable when performance is paramount, particularly for large-scale simulations and leveraging advanced computation facilities like supercomputers. Developed as a TVB-compatible Back-End, TVB C++ seamlessly integrates with the original TVB implementation, facilitating effortless usage. Users can easily configure TVB C++ to execute the same code as in TVB but with enhanced performance and parallelism capabilities. As a consequence, TVB C++ will enable the widespread use of individualized models that will open the possibility of designed tailored solutions at the individual patient level.
(© 2025 The Author(s). Advanced Science published by Wiley‐VCH GmbH.)