• DNA computing: DNA circuits an...

Treffer: DNA computing: DNA circuits and data storage.

Title:
DNA computing: DNA circuits and data storage.
Authors:
Xu H; College of Engineering and Applied Sciences, State Key Laboratory of Analytical Chemistry for Life Science, National Laboratory of Solid State Microstructures, Jiangsu Key Laboratory of Artificial Functional Materials, Chemistry and Biomedicine Innovation Center, Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing 210023, China. ytian@nju.edu.cn., Yu Y; College of Engineering and Applied Sciences, State Key Laboratory of Analytical Chemistry for Life Science, National Laboratory of Solid State Microstructures, Jiangsu Key Laboratory of Artificial Functional Materials, Chemistry and Biomedicine Innovation Center, Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing 210023, China. ytian@nju.edu.cn., Li P; College of Engineering and Applied Sciences, State Key Laboratory of Analytical Chemistry for Life Science, National Laboratory of Solid State Microstructures, Jiangsu Key Laboratory of Artificial Functional Materials, Chemistry and Biomedicine Innovation Center, Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing 210023, China. ytian@nju.edu.cn., Liu S; College of Engineering and Applied Sciences, State Key Laboratory of Analytical Chemistry for Life Science, National Laboratory of Solid State Microstructures, Jiangsu Key Laboratory of Artificial Functional Materials, Chemistry and Biomedicine Innovation Center, Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing 210023, China. ytian@nju.edu.cn., Yan X; College of Engineering and Applied Sciences, State Key Laboratory of Analytical Chemistry for Life Science, National Laboratory of Solid State Microstructures, Jiangsu Key Laboratory of Artificial Functional Materials, Chemistry and Biomedicine Innovation Center, Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing 210023, China. ytian@nju.edu.cn., Zhou Z; College of Engineering and Applied Sciences, State Key Laboratory of Analytical Chemistry for Life Science, National Laboratory of Solid State Microstructures, Jiangsu Key Laboratory of Artificial Functional Materials, Chemistry and Biomedicine Innovation Center, Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing 210023, China. ytian@nju.edu.cn., Tian Y; College of Engineering and Applied Sciences, State Key Laboratory of Analytical Chemistry for Life Science, National Laboratory of Solid State Microstructures, Jiangsu Key Laboratory of Artificial Functional Materials, Chemistry and Biomedicine Innovation Center, Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing 210023, China. ytian@nju.edu.cn.
Source:
Nanoscale horizons [Nanoscale Horiz] 2025 Nov 17; Vol. 10 (12), pp. 3204-3217. Date of Electronic Publication: 2025 Nov 17.
Publication Type:
Journal Article; Review
Language:
English
Journal Info:
Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101712576 Publication Model: Electronic Cited Medium: Internet ISSN: 2055-6764 (Electronic) Linking ISSN: 20556756 NLM ISO Abbreviation: Nanoscale Horiz Subsets: MEDLINE
Imprint Name(s):
Original Publication: [Cambridge, England] : Royal Society of Chemistry, [2016]-
MeSH Terms:
DNA*/chemistry , Computers, Molecular* , Information Storage and Retrieval*/methods
Substance Nomenclature:
9007-49-2 (DNA)
Entry Date(s):
Date Created: 20250915 Date Completed: 20251117 Latest Revision: 20251117
Update Code:
20251118
DOI:
10.1039/d5nh00459d
PMID:
40948194
Database:
MEDLINE

Weitere Informationen

Computation has consistently served as a significant indicator and direction of social development, and volume, speed, and accuracy are critical factors during development. To accelerate this computational process, various advanced technologies and constantly optimized computational methods have been developed, such as upgrading chip design and proposing quantum and photonic computing. Recently, DNA computing, as a unique computational model distinct from traditional methods, offers remarkable advantages and addresses problems that are difficult to solve with conventional computing. By designing DNA molecules and utilizing their spontaneous reactions, specific types of complex problems can be solved, such as combinatorial optimization, traveling salesman, Sudoku and other nondeterministic polynomial time (NP) problems. Based on the spontaneity of reactions, this type of computation exhibits high parallelism, making DNA computing a viable solution for high-complexity problems. This review presents an overview of the theoretical foundations of DNA computing and summarizes three distinct advantages to over traditional computing: high parallelism, efficient storage, and low energy consumption. Furthermore, based on these advantages, we assess the current state of development in two critical branches of DNA computing: DNA circuit and DNA information storage, and provide unique insights for the future development of DNA computing.