Treffer: Progress in the Application of DNA Microarrays.

Title:
Progress in the Application of DNA Microarrays.
Authors:
Lobenhofer, Edward K., Bushel, Pierre R., Afshari, Cynthia A., Hamadeh, Hisham K.
Source:
Environmental Health Perspectives. Sep2001, Vol. 109 Issue 9, p881. 11p. 1 Diagram, 2 Charts, 1 Graph.
Subject Terms:
*Environmental toxicology, *Environmental health, DNA microarrays, Gene expression
Database:
GreenFILE

Weitere Informationen

Microarray technology has been applied to a variety of different fields to address fundamental research questions. The use of microarrays, or DNA chips, to study the gene expression profiles of biologic samples began in 1995. Since that time, the fundamental concepts behind the chip, the technology required for making and using these chips, and the multitude of statistical tools for analyzing the data have been extensively reviewed. For this reason, the focus of this review will be not on the technology itself but on the application of microarrays as a research tool and the future challenges of the field. Key words: DNA chips, gene expression profiling, microarray, toxicogenomics. Environ Health Perspect 109:881-892 (2001). [Online 16 August 2001] http://ehpnetl.niehs.nih.gov/docs/2001/109p881-892lobenhofer/a bstract.html [ABSTRACT FROM AUTHOR]

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